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Gene Expression Literature Summary
Assay
Age
In situ reporter (knock in)
10.5 DPC

11 matching records from 11 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Pitx2  paired-like homeodomain transcription factor 2   (Synonyms: Brx1, Brx1a, Brx1b, Munc30, Otlx2, Pitx2a, Pitx2b, Pitx2c, Ptx2, Rieg, solurshin)
Results  Reference
1J:187280 Campbell AL, Shih HP, Xu J, Gross MK, Kioussi C, Regulation of motility of myogenic cells in filling limb muscle anlagen by Pitx2. PLoS One. 2012;7(4):e35822
1J:332137 Hu H, Duan Y, Wang K, Fu H, Liao Y, Wang T, Zhang Z, Kang F, Zhang B, Zhang H, Huo F, Yin Y, Chen G, Hu H, Cai H, Tian W, Li Z, Dental niche cells directly contribute to tooth reconstitution and morphogenesis. Cell Rep. 2022 Dec 6;41(10):111737
1J:80691 Kioussi C, Briata P, Baek SH, Rose DW, Hamblet NS, Herman T, Ohgi KA, Lin C, Gleiberman A, Wang J, Brault V, Ruiz-Lozano P, Nguyen HD, Kemler R, Glass CK, Wynshaw-Boris A, Rosenfeld MG, Identification of a Wnt/Dvl/beta-Catenin --> Pitx2 Pathway Mediating Cell-Type-Specific Proliferation during Development. Cell. 2002 Nov 27;111(5):673-85
1*J:69854 Liu C, Liu W, Lu MF, Brown NA, Martin JF, Regulation of left-right asymmetry by thresholds of Pitx2c activity. Development. 2001 Jun;128(11):2039-48
1*J:79853 Liu C, Liu W, Palie J, Lu MF, Brown NA, Martin JF, Pitx2c patterns anterior myocardium and aortic arch vessels and is required for local cell movement into atrioventricular cushions. Development. 2002 Nov;129(21):5081-91
1J:317599 Ma HY, Xu J, Eng D, Gross MK, Kioussi C, Pitx2-mediated cardiac outflow tract remodeling. Dev Dyn. 2013 May;242(5):456-68
1*J:117808 Shih HP, Gross MK, Kioussi C, Expression pattern of the homeodomain transcription factor Pitx2 during muscle development. Gene Expr Patterns. 2007 Feb;7(4):441-51
1*J:120320 Shih HP, Gross MK, Kioussi C, Cranial muscle defects of Pitx2 mutants result from specification defects in the first branchial arch. Proc Natl Acad Sci U S A. 2007 Apr 3;104(14):5907-12
1J:216504 Shiratori H, Yashiro K, Iwai N, Oki S, Minegishi K, Ikawa Y, Kanata K, Hamada H, Self-regulated left-right asymmetric expression of Pitx2c in the developing mouse limb. Dev Biol. 2014 Nov 15;395(2):331-41
1J:248849 van Vliet PP, Lin L, Boogerd CJ, Martin JF, Andelfinger G, Grossfeld PD, Evans SM, Tissue specific requirements for WNT11 in developing outflow tract and dorsal mesenchymal protrusion. Dev Biol. 2017 Sep 1;429(1):249-259
1J:203656 Waite MR, Skidmore JM, Micucci JA, Shiratori H, Hamada H, Martin JF, Martin DM, Pleiotropic and isoform-specific functions for Pitx2 in superior colliculus and hypothalamic neuronal development. Mol Cell Neurosci. 2013 Jan;52:128-39

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory